Monacolin Q10 Plus

Often times, along with healthy habits, a balanced diet, and exercise, it becomes necessary to have an extra contribution that helps to reduce the levels of bad cholesterol (LDLc), and balance it with good cholesterol (HDLc).

Naturally present in red yeast rice, the monacolin K it is an active compound that helps maintain normal blood cholesterol levels. With their namesake product, Vitobest® It proposes a food alternative of the highest quality (4% monacolin K) so that you can take full advantage of all its benefits.

Obtained from a yeast (Monascus purpureus) that grows on rice, the red yeast of this cereal contains several active compounds called monacolins, which inhibit the synthesis of cholesterol¹. Monacolin K is the main ingredient, being the most recognized by scientific literature.

Several preclinical and clinical studies define this substance as a potent inhibitor of HMG-CoA reductase (reducer of blood lipids^2,3), and make it the most appropriate dietary alternative to keep blood cholesterol levels stable.

This is also endorsed by the European Food Safety Authority (EFSA) and the European Commission since the year 2012.

Importance of Q10:

• Coenzyme Q10 is a potent antioxidant, an endogenous antioxidant that is part of the energy balance of cells.
• Regular intake of statins (and monacolin is a statin), depletes the body's CoQ10. Although monacolin depletes it less than other statins, an extra supply is necessary.
• As we lose coenzyme Q10, fatigue, muscle weakness and pain may appear.
• It is an essential part of the Krebs cycle (energy production).
• It enhances the action of monacolin, helping to reduce LDL⁴.
• Low levels of Q10 are associated with an increase in arterial stiffness that markedly improves by providing extra Q10⁵.
• Supplementation with CoQ10 helps reduce hypertension and significantly control blood sugar levels^6,7.

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Special warnings: The daily amount of 3 mg of monacolins from red yeast rice or more should not be consumed. It should not be consumed by pregnant or breastfeeding women, children and teenagers under 18 years old or adults over 70 years old. If you experience any health problems, consult your doctor about consuming this product. It should not be consumed along with cholesterol-lowering medication. It should not be consumed if other products containing red yeast rice are already being consumed.

Bibliography:

¹"Red yeast rice in the treatment of hypercholesterolemia". 2012. Martínez Álvarez., J.R., Clinical Nutrition and Hospital Dietetics. 32(2):106-109. Consulted at: http:// www.nutricion.org/publicaciones/revista_2012_32_2/LEVADURA-ROJA.pdf

²"A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough". 2012. Shanes, J.G., Curr Atheroscler Rep. 14(1):33-40.

³"Cardiovascular Disease: C-Reactive Protein and the Inflammatory Disease Paradigm: HMG-CoA Reductase Inhibitors, Alpha-Tocopherol, Red Yeast Rice, and Olive Oil Polyphenols. A Review of the Literature". 2001. Patrick, L. & Uzick, M., Altern Med Rev. 6(3):248-71.

⁴“Young JM, Molyneux SL, Reinheimer AM, Florkowski CM, Frampton CM, Scott RS, George PM, Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long term statin therapy, Atherosclerosis 218 (2011) 188–193. [PubMed: 21640350]

⁵"Effect of Monacolin K and COQ10 supplementation in hypertensive and hypercholesterolemic subjects with metabolic syndrome by Alberto Mazzaa*, Salvatore Lentib, Laura Schiavonc, Ezio Di Giacomod, Monica Tomasic, Roberto Manuntae, Gioia Torinf, Danyelle M. Townsendg, and Domenico Rubelloh."

⁶"Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD, Coenzyme Q10 improves blood pressure and glycemic control: a controlled trial in subjects with type 2 diabetes, Eur. J. Clin. Nutr 56 (2002) 1137–1142. [PubMed: 12428181]

⁷"Singh RB, Niaz MA, Rastogi SS, Shukla PK, Thakur AS, Effect of water-soluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease, J. Hum. Hypertens 13 (1999) 203–208. [PubMed: 10204818].