AyuFlex

AyuFlex, from Vitobest®, it is an aqueous extract of Terminalia chebula, based on the knowledge and principles of the ancient Ayurvedic medicine.

The Terminalia chebula it has great antioxidant power and is very rich in polyphenols and tannins, both responsible for its effectiveness.

AyuFlex® It is a powerful anti-inflammatory helping to effectively inhibit the COX-1, COX-2, and 5-LOX enzymes, mediators of pain and inflammation.

AyuFlex Vitobest® is shown to be very effective in:

• Scientific studies support the effectiveness of AyuFlex® in reducing pain and inflammation^1,2.
• Ayuflex is an essential ally in joint health.

• Helps to improve recovery, act as a pain reliever and inhibit inflammation mediators.
• It improves joint function and mobility, with substantial improvements observed in the WOMAC and VAS indices⁴.

• Contributes to the overall health of the back by reducing inflammation.
• Improvements have also been observed in the WOMAC and VAS indices in this regard⁴.

• AyuFlex® it is also a powerful antioxidant, having an antioxidant capacity of 36,000 µmoles TE7G on the ORAC scale⁵, proving to be very useful also to help reduce oxidative stress.

• It contributes to joint recovery and regeneration, reducing inflammation and repairing damaged cartilage¹.

Their qualities and broad spectrum of effectiveness make it AyuFlex, from Vitobest®, be an indispensable complement to our general health and well-being.

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Bibliography:

¹A randomized, double-blind, placebo-controlled, parallel group clinical study to evaluate the analgesic effect of aqueous extract of Terminalia chebula, a proprietary chromium complex, and their combination in subjects with joint discomfort.

²A randomized, double-blind, placebo-controlled, cross-over study to evaluate the analgesic activity of Terminalia chebula In healthy human volunteers using a mechanical pain model, Venkata Kishan Pokuri, Chiranjeevi Uday Kumar, Usharani Pingali, Department of Clinical Pharmacology and Therapeutics, ICMR Advanced Center for Pharmacodynamics, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India.

³To Tasaduq SA, Singh K, Sethi S, Sharma SC, Bedi KL, Singh J, et al. Hepatocurative and antioxidant profile of HP-1, a polyherbal phytomedicine. Hum Exp Toxicol 2003; 22(12): 639-645.

⁴The WOMAC scale is the questionnaire used to assess outcomes in the lower limb, regarding functionality and quality of life, including pain, stiffness, and mobility. The Visual Analog Scale (VAS) allows measuring the intensity of pain described by the patient with the highest reproducibility among observers. 1- Mild pain if the patient scores the pain as less than 3. 2- Moderate pain if the rating is between 4 and 7. 3- Severe pain if the rating is equal to or greater than 8.

⁵ORAC (Oxygen Radical Absorbance Capacity) is the unit of measurement for the antioxidant power of a substance. By neutralizing free radicals with more than 5,000 ORAC per day, it helps to prevent the formation of its derivatives Peroxynitrite, Simple Oxygen and Hydrogen Peroxide, avoiding oxidative stress and being essential to maintain our health.