Pack No Pain

Pack No Pain



€29.34

Size
  • 60 capsules



€36.72

Size
  • 22 sachets x (15 g)
Flavor



€26.64

Size
  • 90 softgels
€92.70
Quantity
Last items in stock

Pack content

  • UC-II® Collagen + Glucosamine Sulfate & Chondroitin + MSM (OptiMSM®).
  • Additionally, it contains other natural bioactive substances of the highest quality.
  • Supplement recommended for joints.
  • Suitable for people with celiac disease.
  • Capsules free of titanium dioxide.

The improved new formula of ArtiFlex, from Vitobest®, it combines the action of the best active ingredients that contribute to improving joint health, repairing damaged cartilage, and effectively reducing pain and inflammation1.

ArtiFlex, from Vitobest®, contains hydrolyzed collagen UC-II® (Lonza).

 

ArtiFlex 01

 

What makes UC-II® collagen so effective?

  • It resists hydrolysis in the intestine, improving absorption.
  • Intestinal hydrolysis (part of the digestion process) normally removes much of the classic collagen, absorbing only a tiny part.
  • The UC-II® Lonza has a unique mechanism of action that directly stimulates the production of collagen by chondrocytes, which are the cells of the cartilaginous tissue responsible for tissue maintenance and collagen production3.

Why is type II collagen so important in the body?

Type II collagen is the main component of cartilaginous tissues.

Articular cartilage is a highly specialized tissue that covers the bone surfaces that form part of the joints. It is responsible for protecting the bones of the joints and facilitating movement.

The articular cartilage does not have blood vessels, it is nourished by the synovial fluid superficially and by the bone deeply to nourish itself, and has little capacity to regenerate.

Chondrocytes, the only cellular element of cartilage, are responsible for the synthesis and maintenance of the extracellular matrix, which is composed of 80% water and 20% solid matter, with its main components being type II collagen and proteoglycans. Therefore, the contribution of external collagen is vital. UC-II® in order to help recover lost cartilage and as a preventive measure.

 

ArtiFlex 02

 

Clinically proven.

Numerous studies demonstrate the effectiveness of cartilage UC-II®, both in the treatment2 as in prevention.

Reduction in the WOMAC scale2.

  • Greater efficiency of UC-II® in front of glucosamine (Lugo JP, et al. Nutr J. 2016;15:14).

 

ArtiFlex 03

 

The research shows that UC-II® contributes to:

  • Improve the mechanical function of the injured knee.
  • Prevent the deterioration of articular cartilage.

UC-II® Study by Bagi et al.

 

ArtiFlex 04

 

ArtiFlex, from Vitobest®, enhances the action of the cartilage UC-II® adding high-quality active ingredients with proven effectiveness:

  • Glucosamine sulfate8 and chondroitin: they help to recover damaged cartilage5,9.
  • OptiMSM®: effective in mitigating joint pain. It is a powerful natural analgesic and anti-inflammatory agent.5,6.
  • Green-lipped mussel: offers a wide spectrum of Omega 3 fatty acids: EPA, DHA, ALA, SDA, DPA and ETA. The green-lipped mussel helps in processes related to joint inflammation7.
  • Magnesium Bisglycinate (Albion™): vital for the joints.
  • Vitamin C: indispensable for the synthesis of collagen and the fixation of new cartilage.

 

 

ArtiFlex of Vitobest® contributes to:

  • Recover damaged cartilage and acts preventative in joint health.
  • Reduce inflammation and joint pain.
  • Prevent joint injuries and mild rheumatic diseases4.
  • Prevent and recover from sports injuries.

Combined with Curcumin (BCM-95®) or Shilajit from Vitobest® enhances its effectiveness and its anti-inflammatory action.

Vitobest® used for this supplement titanium dioxide-free capsules.

 

Sin dióxido de titanio

 

Bibliography:
1"Bello, AE. and Oesser, S. Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature" [en línea]". Curr Med Res Opin, 2006.
2"Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study James P". Lugo1, Zainulabedin M. Saiyed1 and Nancy E. Lane2.
3"Understanding Collagen Supplements in Arthritis - Immunomodulation with Undenatured Collagen II Versus Cartilage Building with Hydrolysed Collagen II". Varsha Narayanan, Rajesh Gandhi Health and Pharmaceutical Consultant, Dr. Varsha's Health Solutions, Andheri West, Mumbai, India. Orthopedic Surgeon, Gandhi Nursing Home, Andheri West, Mumbai, India.
4"Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers by James P Lugo, Zainulabedin M Saiyed, Francis C Lau, Jhanna Pamela L Molina, Michael N Pakdaman, Arya Nick Shamie and Jay K Udani.
5"Randomized, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis". 2004. Usha, P.R. & Naidu, M.U.R., Drug Clinical Research. Volume 24, Number 6, pages 353–363.
6"Effect of methylsulfonylmethane supplementation on exercise-induced muscle damage and total antioxidant capacity" Barmaki S. et al., 2012.
7"Halpern G. Anti-inflammatory effects of a stabilized lipid extract of perna canaliculus (Lyprinol)". Townsend Letter for Doctors and Patients 2000; 202:109.
8Herrero-Beaumont G et al. "Glucosamine Sulfate in the Treatment of Knee Osteoarthritis Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study Using Acetaminophen as a Side Comparator". Arthritis & Rheumatism 2007;56(2):555-567.
9Kelly GS. "The Role of Glucosamine Sulfate and Chondroitin Sulfates in the Treatment of Degenerative Joint Disease". Altern Med Rev. Feb 1998;3(1):27-39.
  • Synergistic formula for ligament and tendon health.
  • With Tendoforte® Bioactive Collagen Peptides® (GELITA), BCM-95® turmeric extract, Boswelia serrata, hyaluronic acid, Leucine, magnesium bisglycinate (Albion™) and vitamin C.
  • Convenient sachet format.
  • Suitable for people with celiac disease.

TendoFlex Forte, from Vitobest®, it is a synergistic formula of the latest generation with hydrolyzed collagen peptides (Tendoforte® Bioactive Collagen Peptides®) (GELITA), turmeric extract BCM-95®, Boswellia serrata, hyaluronic acid, Leucine, magnesium bisglycinate (Albion™) and vitamin C, which work together for the health of ligaments and tendons.

 

 

Collagen is the most abundant protein in the body.

Collagen is the main component of connective tissue and the most abundant protein in the body (30%).

White connective tissue is everywhere, providing structure and transferring force without breaking.

 

TendoFlex Forte 01

 

Bioactive peptides for maximum efficacy.

Most collagen supplements on the market are composed of hydrolyzed collagen which has very low absorption, slow and bothersome digestion, and little ability to act on specific structures, bones, joints or muscles, having a very reduced efficacy.

TendoFlex Forte, from Vitobest®, incorporates bioactive peptides (Tendoforte® Bioactive Collagen Peptides®) (GELITA) of the latest generation that act directly by stimulating the production and regeneration of collagen in muscles, tendons, and ligaments. These peptides are characterized by a specific molecular weight profile, and with proven optimal stimulation in specific cells1.

Maximum digestibility due to its helical peptide form4, achieving maximum absorption and bioavailability2.

 

TendoFlex Forte 02

 

Triple action pathway on specific cells1.

Due to their specific composition, bioactive peptides act on target cells (bone, cartilage, muscles or tendons), in three phases, compared to the two phases of common hydrolysates:

  1. Stimulating the cell.
  2. RNA translation.
  3. Biosynthesis of the extracellular matrix.

TendoFlex Forte 03

 

TendoFlex Forte, a formula that hits the bullseye directly.

Not all collagen supplements are the same and their effectiveness directly depends on reaching and stimulating the correct structures and cells. The specific formula of TendoFlex Forte It directly stimulates the fibroblasts of muscle and tendon cells, achieving maximum effectiveness.

 

TendoFlex Forte 04

 

TendoFlex Forte, from Vitobest®, acts directly on the muscular and tendinous extracellular matrix.

Muscles do not exist by themselves. Connective tissue forms the support for each muscle fiber and plays a vital role in physical activity, transferring strength and movement. This matrix is entirely composed of collagen and is the one that gets injured in muscle and tendon pathologies. By properly nourishing it with TendoFlex Forte, it helps prevent and minimize sports injuries, and improve muscle efficiency and strength ratio.

 

TendoFlex Forte 05

 

Maximum efficiency.

The advanced formula of TendoFlex Forte It acts synergistically, effectively helping to prevent overloads and muscle injuries and contributing to a faster and more effective recovery. It reduces inflammatory processes and efficiently contributes to the regeneration and recovery of tissues.

  • Tendoforte®: bioactive peptides of maximum bioavailability and efficacy that directly stimulate muscle and tendon cells to produce collagen.
  • BCM-95®: High bioavailability turmeric extract that helps reduce inflammation.
  • Boswellia serrata: powerful natural anti-inflammatory.
  • Hyaluronic Acid: contributes to improving collagen fixation.
  • L-Leucine: contributes to the recovery of damaged muscle tissue.
  • Vitamin C: helps to improve collagen fixation.

TendoFlex Forte 06

Benefits of TendoFlex Forte Vitobest®:

  • Strengthens tendons and ligaments3.
  • Protects from overloads and micro-tears in sports5.
  • It significantly accelerates recovery and the return to training and competition3.
  • Synergistic anti-inflammatory action of boswellia and BCM-95® that enhances the recovery of damaged tissue.
  • Hyaluronic acid improves collagen fixation.
  • Absence of gastric problems and maximum bioavailability2.4.
  • Very pleasant taste and effectiveness with lower doses.

 

 

Backed by scientific studies.

Scientific studies support the effectiveness of TendoFlex Forte, improving recovery after injuries by speeding up the return to exercise3 and preventing injuries from overloading and repetition5.

 

TendoFlex Forte 07

 

TendoFlex Forte, from Vitobest®, it comes in a convenient box format with 22 sachets of 15 g.

 

Articulares Innovate

 
Bibliography:
1Interaction of the α2A domain of integrin with small collagen fragments. Hans-Christian Siebert, Monika Burg-Roderfeld, Thomas Eckert, Sabine Stötzel, Ulrike Kirch, Tammo Diercks, Martin J. Humphries, Martin Frank, Rainer Wechselberger, Emad Tajkhorshid, Steffen Oesser.
2Srivastava 2017 p.457; Miner-Williams et al. 2014; Wada and Lönnerdal 2014 and Lorkowski 2012.
3Improvement of Functional Ankle Properties Following Supplementation with Specific Collagen Peptides in Athletes with Chronic Ankle Instability. Patrick Dressler, Dominic Gehring, Denise Zdzieblik, Steffen Oesser, Albert Gollhofer and Daniel König. University of Freiburg, Department of Sport and Sport Science, Freiburg, Germany CRI, Collagen Research Institute, Kiel, Germany.
4Composition and properties of peptides that survive standardized in vitro gastro-pancreatic digestion of bovine milk. Davide Tagliazucchi, Ahmed Helal, Elena Verzelloni, Andrea Bellesia, Angela Conte.
5Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients. Stephan F.E. Praet, Craig R. Purdam, Marijke Welvaert, Nicole Vlahovich, Gregg Lovell, Louise M. Burke, Jamie E. Gaida, Silvia Manzanero, David Hughes and Gordon Waddington.
  • 50% DHA and 10% EPA.
  • 1000 mg of concentrated fish oil per softgel.
  • TG (Triglycerides).
  • High content of Omega 3 fatty acids.
  • Guarantee and quality of Goldenomega®.
  • Suitable for people with celiac disease.

Pure Omega 3 DHA, from Vitobest®, it is a supplement of Omega 3 fatty acids concentrated, of the most high quality and purity obtained by double molecular distillation, which guarantees a virtually free from impurities, heavy metals and with an outstanding sensory profile. It is a specific combined formula for eye and brain health. In addition, it comes with the guarantee and quality of Goldenomega®.

 

Goldenomega 01

 

What sets Pure DHA apart from Vitobest.

  • Outstanding sensory profile. Fatty acids virtually without smell, without taste, and without the typical bothersome gastric reflux.

 

Pure Omega 3 DHA 01

 

  • Product of extreme purity and quality. Pure Omega 3 DHA, from Vitobest®, it presents extremely low levels of heavy metals and contaminants and impurities.
  • Product in the form of triglyceride, achieving maximum bioavailability, greatly increasing absorption and benefits compared to other presentations of fatty acids1.
  • Very low oxidation parameters. This allows to keep its qualities intact, with values close to those of its production for a long time.

 

Pure Omega 3 DHA 02

 

Why do we need an extra intake of Omega 3 fatty acids?

  • The body is not able to synthesize it and it must be provided through diet.
  • There is an excess of Omega 6 in our diet.
  • Our diet is increasingly scarce in Omega 3 fatty acids, not achieving a proper intake.
  • It is a supplement that is widely proven to provide numerous health benefits2.

Highest quality, efficiency and innovation.

  • The triglyceride form increases the efficiency and bioavailability and effectiveness compared to other presentations (ethyl esters)1.

 

Pure Omega 3 DHA 03

 

  • Greater absorption in the intestine1.
  • Triglyceride is a natural form of lipids and our body is accustomed to them.
  • Without gastric reflux.

Goldenomega 02

Pure Omega 3 DHA, balanced formula for eye health and the brain.

DHA, along with arachidonic acid, is the polyunsaturated fatty acid found in the highest concentration in nerve tissue. DHA plays a significant role in the formation and function of the nervous system, particularly in the brain. 60-65% of the brain's total lipids are polyunsaturated fatty acids, and of this percentage, over 85% is made up of DHA (35-40%) and arachidonic acid (40-50%).

  • Contributes 500 mg of DHA and 100 mg of EPA for softgel.
  • It helps cognitive function and is useful in preventing degenerative diseases such as Alzheimer's and dementia10.
  • It is an important supplement in the treatments and prevention of depression11.
  • Prevents oxidative stress and inflammation4.
  • Eye health8.

 

 

Product Claims:

  • An intake of 250 mg of eicosapentaenoic and docosahexaenoic acids contributes to the normal functioning of the heart.
  • An intake of 250 mg of docosahexaenoic acid helps to maintain the normal functioning of the brain.
  • An intake of 250 mg of docosahexaenoic acid contributes to the maintenance of normal vision.

 

CapsuLIQ

 

Bibliography:
1Bioavailability of marine n-3 fatty acid formulations. J. Dyerberg a,n , P. Madsen b, J.M. Møller c, I. Aardestrup b, E.B. Schmidt.
2"Hornstra G (2012) Omega-3 long chain and health benefits. Maastricht University Translation from the original: Anselmino Catherine Centre for Vitamin Study and Information Roche Vitamins France Nevilly-Sur-Seine 56pp."
3Simopoulos AP (2015) The importance of omega-6/omega-3 essential fatty acids. Biomed Pharmacother 56:365-379.
3Harris WS (2007). Omega-3 fatty acids and cardiovascular disease: a case for omega-3 index as a new risk factor. Pharmacol Res 55 (Suppl 3), S217–S223.
4Docosahexaenoic acid reduces macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. Oliver E, McGillicuddy FC, Harford KA, Reynolds CM, Phillips CM, Ferguson JF, Roche HM. J Nutr Biochem. 2012 Sep;23(9):1192-200. doi: 10.1016/j.jnutbio.2011.06.014. Epub 2011 Dec 1. PMID: 22137266.
5Docosahexaenoic acid regulates vascular endothelial cell function and prevents cardiovascular disease. Kazuo Yamagata.
6The effect of omega-3 unsaturated fatty acids on non-alcoholic fatty liver disease: A systematic review and meta-analysis of RCTs. Le Ya, Man Yuan, Linchun Wang.
7Gawrisch K, Eldho N, Holte L. The structure of DHA in phospholipid membranes. Lipids 2003; 38: 445-452.
8Modulating Contact Lens Discomfort with Anti-Inflammatory Approaches: A Randomized Controlled Trial. Laura E Downie, Anne Gad, Chinn Yi Wong, John Henry V Gray, Weiguang Zeng, David C Jackson, Algis J Vingrys.
10Effects of N-3 Polyunsaturated Fatty Acids on Dementia. Hidekatsu Yanai.
11Role of Omega-3 Fatty Acids in the Etiology, Treatment, and Prevention of Depression: Current Status and Future Directions. Robert K McNamara.

Pack No Pain

€92.70